Genotoxicity tests refer to in vitro and in vivo assays used to detect direct or indirect induction of genetic damage by test substances through different mechanisms of DNA damage and fixation of the damage. DNA damage that occurs in the forms of gene mutations, chromosomal damage, recombination, and chromosome number changes is heritable and contribute to multistage development of malignant tumors. Assays on genotoxicity can be divided into three categories by endpoints of gene mutations, chromosomal aberration, and DNA damage. As no single assay can detect all endpoints, a battery of tests is adopted for comprehensive evaluation of the potential genotoxic risks of the test substance.

IPHASE has developed a variety of genotoxicity assay kits, including Ames Kit, Mini Ames Test Kit, TK/HGPRT Gene Mutation Kit, Chromosomal Aberration Kit, Micronucleus Test Kit, and Comet Assay Kit. Key components such as Liver S9 Activation System, Giemsa Staining reagents are also offered. These products are designed to facilitate testing procedures by eliminating the tedious preparation process and improve study reliability with well-established product specification.