Contracted research services are offered based on our in vitro and in vivo testing platforms developed in house. We combine our specialized knowledge in research products development with our more than 10 years practice in the field to provide clients professional and customized services. Choose from out service portfolio and discuss with our experts of your individual needs, you will get our prompt, professional and cost-effective services.
Gel filtration chromatography
Ion exchange chromatography
Bacteria (E. coli) Expression
Mammalian Cells (CHO, HEK293) Transient Expression
Antibodies neutralizing activity
Cell proliferation/apoptosis detection
Antigen immunization in mice and rabbits
Cell fusion and hybridoma subclones screening by WB, ELISA, FACS
Heavy chain and light chain sequencing and humanization
Validation by binding assay, KD, cell-based assay
Roller bottle production and purification
Cryopreservation and cell banking
Anti-idiotype antibody development
ELISA assay for PK and ADA development and validation
Affinity measurement by Blitz
Epitope characterization by ELISA and WB
Cell-based potency assays: inhibition of cell proliferation, kinase activation (phosphorylation WB), SAA secretion, CCL17 and CCL21 induction in PBMC
iPhase Biosciences will rapidly respond to your needs and commits fast turnaround and high efficiency deliverables. With an extensive range of antibodies and mature cell isolation methods, we offer you desired cells with assured high-quality and quantity.
We offer a comprehensive in vitro service of A (absorption), D, (disposition), M (metabolism), and E (excretion) to pharmaceutical companies. Our ADME assays come in a variety of formats to suit different drug discovery and development stages.
• In vitro permeability
• Plasma stability assay
• Plasma protein binding
• In vitro metabolic stability
• Bacterial reverse mutation test (AMES)
• In Virto
Mammalian Chromosomal Aberration Test
• In Virto
Mammalian Cell Gene Mutation Test
• Comet Assay
Our bioanalytical facility has the state-of-art instruments, including LC-MS/MS, GC-MS, ICP-MS to develop analytical methods for organic, inorganic (metals), and gaseous compound in biologic samples. Activities of method validation and analysis meet the requirement of GLP and GCP.
Method validation of sensitivity, linearity, specificity, precision, and accuracy etc.